• Users Online: 155
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2021  |  Volume : 11  |  Issue : 4  |  Page : 81-84

Prevalence of glucose-6-phosphate dehydrogenase deficiency among neonates with hyperbillirubinemia in the West of Iran


1 Department of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2 Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

Correspondence Address:
Ensiyeh Jenabi
Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan
Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aihb.aihb_12_21

Rights and Permissions

Introduction: Hyperbilirubinemia is a common complication among neonates. The objective of this cross-sectional study was the prevalence of glucose 6-phosphate dehydrogenase (G6PD) deficiency among neonates with hyperbilirubinemia in the west of Iran. Materials and Methods: In this retrospective cross-sectional study, the records of neonates with hyperbilirubinemia who were hospitalised in Hamadan located in the west of Iran, from 2011 to 2016 were reviewed. After reviewing and studying each of the mentioned files, the necessary information was entered in the relevant checklists. Then, the neonates were divided into two groups, including the group with G6PD enzyme deficiency in the case study group and the G6PD enzyme-free group in the control study group. All statistical analyses were conducted in SPSS version 21 software and P < 0.05 was statistically considered significant. Results: A total of 1545 neonates with hyperbilirubinemia was reviewed. Among them, 40 neonates were in the case group and 1505 were in the control group. The prevalence of G6PD deficiency in the present study was 2.58% among neonates with hyperbilirubinemia which has a similar gender distribution. There were statistically significant differences between case and control groups based on total bilirubin, direct bilirubin, reticulocyte count, time of appearance of jaundice, duration of receiving phototherapy and hospitalisation (P < 0.05). Conclusion: We proposed that cord blood G6PD screening be conducted among neonates. This can be affected in identifying G6PD-deficient neonates who might require a longer hospital stay after birth, with monitoring of their serum bilirubin before and after discharge.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed202    
    Printed8    
    Emailed0    
    PDF Downloaded23    
    Comments [Add]    

Recommend this journal